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用血卟啉衍生物(HpD)作为光敏药物的光动力学疗法(PDT)已愈来愈多地用于恶性肿瘤的局部治疗中。这种技术的成功是由于HpD在肿瘤细胞中的积聚程度大于正常细胞,当肿瘤细胞中的HpD用红光敏化时,吸收足够的能量引起肿瘤细胞被杀死的结果。
Photodynamic therapy (PDT) using hematoporphyrin derivative (HpD) as a photosensitizer has been increasingly used in the local treatment of malignant tumors. The success of this technique is due to the fact that HpD accumulates to a greater extent in tumor cells than normal cells and absorbs enough energy to cause tumor cells to be killed when HpD in the tumor cells is sensitized with red light.