论文部分内容阅读
目的:对高尿酸血症和冠状动脉疾病及其严重程度的相关性进行研究分析。方法:选取我院2012年1月~2013年12月接收治疗的80例经冠状动脉造影证实主要分支管腔狭窄>50%或者至少有一支冠状动脉的患者作为研究组,并将80例冠状动脉狭窄≤50%或者冠状动脉管腔无狭窄的患者作为对照组。结果:女性和男性的体重指数、高血压患病率、高脂血症患病率以及糖尿病患病率对比(p<0.05);男性吸烟率高于女性(p<0.01);男性的血清肌酐与尿酸浓度高于女性(p<0.01)。男性和女性的年龄以及家族史等资料对比(p>0.05);高尿酸血症和冠状动脉之间存在线性关系,血清尿酸程浓度不断升高,患者冠状动脉数量在男性或者女性中依然存在相关性,且在研究患者中,高尿酸血症和冠状动脉疾病的严重程度之间具有相关性,仅存在于男性患者中。结论:高尿酸血症和冠状动脉疾病和其严重程度具有一定的相关性。
Objective: To study the correlation between hyperuricemia and coronary artery disease and its severity. Methods: Eighty patients undergoing coronary artery angiography with primary branch lumen stenosis> 50% or at least one coronary artery were enrolled in our hospital from January 2012 to December 2013. The coronary arteries Patients with stenosis ≤50% or without coronary stenosis were selected as control group. Results: The body mass index, the prevalence of hypertension, the prevalence of hyperlipidemia and the prevalence of diabetes in both men and women (p <0.05), and the smoking rate in men were higher than those in women (p <0.01). Serum creatinine With uric acid concentrations higher than females (p <0.01). Male and female age and family history and other data (p> 0.05); there is a linear relationship between hyperuricemia and coronary artery, serum uric acid concentration continuously increased, the number of patients with coronary artery in men or women still related And there was a correlation between hyperuricemia and the severity of coronary artery disease in study patients, only in male patients. CONCLUSIONS: Hyperuricemia is associated with the severity of coronary artery disease.