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为了探讨小气道形态学变化与肺功能特别是闭合总量的关系,并进而明确闭合总量增高是否反映流速的降低,作者对34例死后48小时(1例除外)离体人肺进行了观察。全部病例均无COPD病史,经大体或显微镜检查除肺气肿外,没有或仅有轻度肺实质损害,其中男性20例,女性14例。实验前先以20～22cmH_2O压力使肺充张和回缩,然后分别以经肺压20cmH_2P和OcmH_2O时肺容量为肺总量(TLC)和残气量
In order to explore the relationship between small airway morphological changes and lung function, especially the total volume of closure, and then clear whether the increase in total closure reflects the reduction of flow rate, the authors of 34 patients died 48 hours after the death (one case) Observed. All cases had no history of COPD, except for emphysema, gross or microscopic examination, there was no or only mild pulmonary parenchymal damage, including 20 males and 14 females. Before the experiment, the lungs were inflated and deflated at a pressure of 20-22cmH 2 O, and then the lung volume (20cmH 2 P and OcmH 2 O 2) was taken as total lung volume (TLC) and residual volume