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地方性氟中毒(地氟病)是一种地球化学性疾病。其临床表现关节疼痛、肢体麻木、运动功能受限、重者瘫痪生活不能自理等,严重的危害着病区人民的身体健康。吉林省从70年代开始试制了10多种方剂治疗地氟病均取得了不同程度的疗效。因此,筛选出高效方剂对地氟病的治疗将起到积极的推进作用。 从整理和统计的资料上看各地病例的选择均为具有典型的临床症状和体征,经X线拍片,化验检查确诊的氟中毒患者。并注意到性别、年龄和临床Ⅰ、Ⅱ、Ⅲ度氟骨症的分型,当地水氟含量均在3.Omg/L以上。疗效判定标准以原中地办颁布的标准为依据,多数方剂在改水后应用,少数方剂在改水前或同时进行的。总的治疗原则是减少氟的吸收,增强机体抵抗力,促进氟的排泄及对症治疗。
Endemic fluorosis (deposition fluorosis) is a geochemical disease. The clinical manifestations of joint pain, numbness of the limbs, limited motor function, and severe self-care can not take care of themselves, seriously endanger the health of people in the ward. In the Jilin Province, from the 1970s onwards, more than 10 kinds of prescriptions have been used in the treatment of endemic fluorosis and have achieved different degrees of efficacy. Therefore, the screening of effective prescriptions for the treatment of desflurane will play a positive role in promoting. From the data of sorting and statistics, the selection of cases from all parts of the country is typical of patients with fluorosis who have typical clinical symptoms and signs, who have been diagnosed with X-rays and laboratory tests. Also note that gender, age and clinical classification of I, II, and III degrees of skeletal fluorosis, the local water fluoride content were above 3.Omg/L. The therapeutic efficacy criteria were based on the standards promulgated by the former China Office. Most formulas were applied after the water was changed, and a few formulas were taken before or while the water was changed. The general principle of treatment is to reduce the absorption of fluoride, enhance body resistance, promote the excretion of fluoride and symptomatic treatment.