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目的探讨苯那普利联合胺碘酮治疗冠心病慢性阵发性房颤的临床疗效。方法 44例冠心病慢性阵发性房颤患者,依据入院编号随机分为观察组和对照组,各22例。对照组患者给予胺碘酮,观察组在对照组的基础上增用苯那普利。比较两组临床疗效。结果治疗后,观察组显效率为54.55%,总有效率为90.91%,均高于对照组的22.73%、63.64%,差异具有统计学意义(P<0.05)。观察组患者左房内径明显未发生明显改变,优于对照组,差异具有统计学意义(P<0.05),同时观察组有1例转化为永久性房颤,对照组6例转化为永久性房颤,组间比较差异具有统计学意义(P<0.05)。结论临床上在治疗冠心病慢性阵发性房颤时,可以采用苯那普利联合胺碘酮的治疗方法 ,能够显著改善患者的各项临床症状,应当在临床上予以大力推广。
Objective To investigate the clinical efficacy of benazepril combined with amiodarone in the treatment of chronic paroxysmal atrial fibrillation in patients with coronary heart disease. Methods Forty - four patients with chronic paroxysmal atrial fibrillation with coronary heart disease were randomly divided into observation group and control group according to admission numbers, and each group had 22 cases. Amiodarone was given to patients in the control group, and benazepril was added to the observation group on the basis of the control group. The clinical efficacy of the two groups were compared. Results After treatment, the effective rate was 54.55% in the observation group and the total effective rate was 90.91%, which was significantly higher than that of the control group (22.73%, 63.64%, P <0.05). In the observation group, the left atrial diameter was significantly changed, which was better than that in the control group (P <0.05). In the observation group, 1 patient was transformed into permanent atrial fibrillation and 6 patients in the control group were transformed into permanent Tremor, the difference between the groups was statistically significant (P <0.05). Conclusion In the treatment of chronic paroxysmal atrial fibrillation in coronary heart disease, benazepril combined with amiodarone treatment can significantly improve the clinical symptoms of patients, it should be vigorously promoted in the clinic.