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在健康女性体内对不同剂量地塞米松的药物动力学以及药物对内源性可的松分泌的影响进行研究。血浆中地塞米松和可的松浓度均用放射免疫法测定。结果表明,口服给药0.5,1.5mg 和肌注3.0mg 后
The pharmacokinetics of different doses of dexamethasone and the effects of drugs on the secretion of endogenous cortisone were studied in healthy women. Plasma dexamethasone and cortisone concentrations were measured by radioimmunoassay. The results showed that oral administration of 0.5, 1.5mg and intramuscular injection of 3.0mg