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用人喉鳞癌组织直接接种于裸鼠，建立了一株裸鼠移植瘤株，命名为ＨＬＣ＿（１４）（取自Ｈｕ－ｍａｎＬａｒｙｎｇｅａｌＣａｎｃｅｒ）。鼠间传代２５代，历时２年多，生长稳定，潜伏期短，鼠间移植成功率达１００％。光镜和电镜下形态与原发瘤相似，染色体分析显示人类肿瘤染色体特点，免疫组化检测细胞内角蛋白反应阳性，显示为上皮来源的肿瘤。平阳霉素治疗的实验研究表明：平阳霉素对ＨＬＣ＿（１４）有明显的作用，抑制率为９０．７％。
Human laryngeal squamous cell carcinoma was inoculated directly into nude mice and a nude mouse transplanted tumor was established and named as HLC_ (14) (taken from Hu-man Laryngeal Cancer). Rats passage 25 generations, which lasted more than two years, stable growth, short incubation period, the success rate of 100% transplanted mice. Light microscope and electron microscopy morphology similar to the primary tumor, chromosome analysis showed the characteristics of human tumor chromosomes, immunohistochemical detection of intracellular keratin reaction was positive for epithelial tumors. Pingyangmycin treatment of experimental studies show that: Pingyangmycin HLC_ (14) has a significant effect, the inhibition rate of 90.7%.