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目的评估布地奈德雾化吸入治疗小儿急性喉炎中的可行性。方法选取我院2014年5月~2016年5月收治的小儿急性喉炎患儿80例,依据随机数字表法将这些患儿分为布地奈德雾化吸入组(布地奈德组,n=40)和甲泼尼龙静脉滴注组(甲泼尼龙组,n=40),对两组患儿的急性喉炎典型症状评分、消失时间、住院时间及临床疗效进行统计分析。结果布地奈德组患儿的呼吸困难、犬吠样咳嗽、声嘶、喉鸣评分均显著低于甲泼尼龙组(P<0.05),呼吸困难、犬吠样咳嗽、声嘶、喉鸣消失时间及住院时间均显著短于甲泼尼龙组(P<0.05),治疗的总有效率97.5%(39/40)显著高于甲泼尼龙组75.0%(30/40,P<0.05)。结论布地奈德雾化吸入较甲泼尼龙静脉滴注治疗小儿急性喉炎更能有效改善患儿的急性喉炎典型症状,缩短其消失时间及住院时间,提高临床疗效,具有较高的可行性。
Objective To evaluate the feasibility of inhalation of budesonide in the treatment of acute laryngitis in children. Methods Eighty children with acute laryngitis in our hospital from May 2014 to May 2016 were randomly divided into three groups: budesonide inhalation group (budesonide group, n = 40) and methylprednisolone intravenous drip group (methylprednisolone group, n = 40). The typical symptoms of acute laryngitis score, disappearance time, length of hospital stay and clinical efficacy of two groups were statistically analyzed. Results Breathing difficulties, bark-like cough, hoarseness, and laryngopharyngeal score in the budesonide group were significantly lower than those in the methylprednisolone group (P <0.05), dyspnea, cough, barking, The hospitalization time was significantly shorter than that of methylprednisolone group (P <0.05). The total effective rate of treatment was 97.5% (39/40), which was significantly higher than that of methylprednisolone group (75.0%, 30/40, P <0.05). Conclusion Budesonide inhalation than methylprednisolone intravenous infusion of children with acute laryngitis is more effective in improving the typical symptoms of acute laryngitis in children, to reduce its disappearance time and hospital stay, improve clinical efficacy, with high feasibility .