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目的探讨前列腺癌病理分级、临床分期与血清前列腺特异抗原(PSA)的关系。方法选取2012年1月至2014年2月开封县第一人民医院治疗的前列腺癌患者73例,所有患者均经过病理学检查,并将所有切片进行病理分级与临床分期,并对患者的血清PSA进行检测,采用Spearman等级相关分析的前列腺癌病理分级、临床分期与血清PSA的关系。结果前列腺癌患者血清PSA值越高,恶性程度越高;前列腺癌的病理分级与血清PSA呈正相关,临床分期也与血清PSA呈正相关。结论血清PSA对临床诊断具有重要意义,其不仅是前列腺癌病理分级、临床分期的重要指标,也可作为判断前列腺癌患者预后情况指标之一。
Objective To investigate the relationship between pathological grade and clinical stage of prostate cancer and serum prostate specific antigen (PSA). Methods From January 2012 to February 2014, 73 cases of prostate cancer were treated in Kaifeng First People’s Hospital. All the patients were pathologically examined. All the sections were pathologically graded and staged. The serum PSA To detect, using Spearman rank correlation analysis of prostate cancer pathological grade, clinical stage and serum PSA. Results The higher the serum PSA was, the higher the malignancy was. The pathological grade of prostate cancer was positively correlated with serum PSA, and the clinical stage was also positively correlated with serum PSA. Conclusions Serum PSA is of great significance in clinical diagnosis. It is not only an important index of pathological grade and clinical staging of prostate cancer, but also a prognostic indicator of prostate cancer.