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目的了解河南省驻马店市“HIV单阳”夫妻阴性配偶HIV血清阳转率及HBV、HCV、梅毒感染现状。方法“HIV单阳”夫妻是指夫妻双方中只有一方呈HIV抗体阳性,另一方为阴性。收集“HIV单阳”夫妻成员HIV抗体检测结果及其他相关信息,采集夫妻中HIV阴性配偶的血标本,并检测其HIV、HBV、HCV及梅毒感染状况。结果该市现有“HIV单阳”夫妻4 301对,本次调查共采集“HIV单阳”夫妻阴性配偶血样3 842份,问卷调查3 738人。最近一次性生活安全套使用率为93.1%,85.9%的HIV感染者已发展为艾滋病病人,抗病毒治疗率为77.8%。经检测有50人HIV抗体阳转,血清阳转率为0.65/100人年,抗-HCV阳性率为31.1%、梅毒阳性率为0.2%、乙型肝炎表面抗原(HBsAg)阳性率为5.4%、乙肝“大三阳”(HBsAg、HBeAg、HBcAb均阳性)率为0.8%,乙肝“小三阳”(HBsAg、HBeAb、HBcAb阳性)率为2.9%。结论驻马店市“HIV单阳”夫妻配偶的血清HIV抗体阳转率较低。建议继续加强对该人群的随访、定期检测CD4细胞计数及病毒载量,夫妻间性生活时坚持使用安全套,以控制HIV性传播。
Objective To understand the seroconversion rate of HIV seropositive HIV seropositive women and the status of HBV, HCV and syphilis infection in Zhuangdian City, Henan Province. Method “HIV single Yang ” couple is only one side of the couple was HIV antibody positive, the other is negative. Collecting HIV antibody test results and other related information from HIV / AIDS HIV / AIDS couple members, collecting blood samples of HIV-negative spouses among couples and detecting HIV, HBV, HCV and syphilis infection status. Results There were 4 301 pairs of “HIV single positive couple” in the city. A total of 3 842 blood samples of “HIV single positive couple” negative spouse were collected in this survey and 3 738 were surveyed. The most recent one-time condom use rate was 93.1%. 85.9% of HIV-infected persons had developed AIDS and the anti-virus treatment rate was 77.8%. After detecting 50 cases of HIV positive seroconversion, seroconversion rate of 0.65 / 100 person-years, anti-HCV positive rate was 31.1%, syphilis positive rate was 0.2%, hepatitis B surface antigen (HBsAg) positive rate was 5.4% , HBsAg, HBeAb and HBcAb were all 0.8% and HBsAg, HBeAb and HBcAb were 2.9%. Conclusion The HIV seroconversion rate of spouses in Zhumadian City was lower than that of spouses in HIV-positive couples. It is recommended to continue to strengthen the follow-up of the population, regular testing of CD4 cell counts and viral load, marital sex between the couple insist on the use of condoms to control HIV transmission.