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肝纤维化是造成肝功能异常和影响慢性肝病预后的重要因素,亦是慢性肝病发展至肝硬化的必经阶段。其病理特征为汇管区大量纤维组织增生,但无假小叶和再生结节形成,并可逆转至正常。因此,尽早采取有效的抗纤维化治疗是防止肝硬化发生的重要措施之一。常用的抗肝纤维化药物如下。 1.皮质类固醇:能减少胶原基因的转录和增加前胶原mRNA的降解,同时抑制肝内炎症反应,去除诱发肝纤维增生的因素。据笔者体会,激素对女性
Liver fibrosis is an important factor that contributes to liver dysfunction and affects the prognosis of chronic liver disease. It is also a necessary stage for the development of chronic liver disease to cirrhosis. The pathological features of the portal area a large number of fibrous tissue proliferation, but no false lobules and regenerative nodules, and can be reversed to normal. Therefore, as soon as possible to take effective anti-fibrosis treatment is one of the important measures to prevent the occurrence of cirrhosis. Common anti-liver fibrosis drugs are as follows. 1. Corticosteroids: can reduce collagen gene transcription and increase the degradation of procollagen mRNA, while inhibiting intrahepatic inflammatory response, the removal of liver fibrosis induced factors. According to my experience, hormones on women