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目的分析1991-2005年福州市区女性乳腺癌发病趋势,为制定防治措施提供科学依据。方法从福建省肿瘤防治办公室获取女性乳腺癌的病例资料,根据人口普查资料中性别、年龄构成推算各年份分性别、年龄组人口数,计算粗发病率、世界人口标化发病率和各年龄组发病率,采用对数线性回归法计算发病率的年度变化百分比(APC),并用病例数进行加权计算。结果 1991-2005年福州市区共有2 812例女性乳腺癌新发病例。发病呈现明显的上升趋势,标化发病率从1991-1992年的18.44/10万上升至2003-2005年的32.64/10万,上升了77.01%,年变化百分率为5.369%(P=0.001)。45~54岁、55~64岁和65~74岁3个年龄段的发病率增长趋势显著,APC分别为4.873%、6.423%和9.512%(P<0.05)。结论福州市区女性乳腺癌的发病率呈明显的上升趋势,应加强乳腺癌防治,提倡健康的生活方式和合理饮食结构。
Objective To analyze the incidence of breast cancer in Fuzhou urban areas from 1991 to 2005 and provide scientific evidence for the prevention and control measures. Methods The cases of female breast cancer were obtained from the Fujian Provincial Office of Cancer Prevention and Control. According to the sex, age and composition of census data, the population of each gender and age group was calculated, the incidence of crude disease, the world population standardized incidence and age groups Incidence rates were calculated using the log-linear regression method to calculate the annual percentage change (APC) of morbidity and weighted by the number of cases. Results A total of 2 812 new cases of breast cancer were found in Fuzhou urban area from 1991 to 2005. The incidence showed a marked upward trend. The standardized incidence increased from 18.44 / 100,000 in 1991-1992 to 32.64 / 100,000 in 2003-2005, up 77.01%. The annual percentage change was 5.369% (P = 0.001). The incidence rates of 45-54 years old, 55-64 years old and 65-74 years old were significantly increased with APC of 4.873%, 6.423% and 9.512%, respectively (P <0.05). Conclusions The incidence of breast cancer in Fuzhou urban area shows a clear upward trend. Prevention and treatment of breast cancer should be strengthened to promote healthy life style and reasonable dietary structure.