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目的分析部分肝功能指标联合血清同型半胱氨酸(Hcy)检测在肝病诊断中的可行性。方法选取2015年1月-2016年6月信宜市人民医院诊治的62例各类肝病患者为观察组,并从同期健康体检者中选取62例自愿参与者为对照组,两组参与研究对象均接受肝功能以及血清Hcy检测,并对两组的检测结果进行比较。结果观察组的总胆固醇(TC)、甘油三酯(TG)、血清丙氨酸转氨酶(ALT)和天冬氨酸转氨酶(AST)和Hcy水平均显著高于对照组,差异均有统计学意义(P<0.05)。观察组急性病毒性肝炎(AVH)、慢性病毒性肝炎(CVH)、肝炎性肝硬化(HLC)、酒精性肝炎(AH)和原发性肝癌(HCC)患者的部分肝功能指标均高于对照组,但组内差异无统计学意义(P>0.05)。结论部分肝功能指标联合血清Hcy检测对于肝病的诊断具有重要的价值,切实可行,为患者的临床治疗提供科学依据,值得临床推广。
Objective To analyze the feasibility of detecting some liver function indexes and serum homocysteine (Hcy) in the diagnosis of liver disease. Methods Sixty-two patients with liver disease diagnosed and treated in Xinyi People’s Hospital from January 2015 to June 2016 were selected as the observation group, and 62 volunteers from the same period were selected as the control group. The two groups participated in the study All received liver function and serum Hcy test, and the test results of the two groups were compared. Results The levels of total cholesterol (TC), triglyceride (TG), serum alanine aminotransferase (ALT), aspartate aminotransferase (AST) and Hcy in the observation group were significantly higher than those in the control group (P <0.05). In the observation group, some liver function indexes in patients with acute viral hepatitis (AVH), chronic viral hepatitis (CVH), hepatic cirrhosis (HLC), alcoholic hepatitis (AH) and primary liver cancer (HCC) were higher than those in the control group , But there was no significant difference within the group (P> 0.05). Conclusion Some of the indexes of liver function combined with serum Hcy test have important value for the diagnosis of liver disease. They are feasible and provide a scientific basis for the clinical treatment of patients and worthy of clinical promotion.