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多囊肝是常染色体显性多囊性肾病(ADPKD)的一种常见表现。有关肝囊肿形成与肾囊肿以及其他肾外表现的关系尚未见资料报道,为确定年龄、性别、妊娠、肾功能、肾囊性变程度及其他肾外表现与肝囊性病的关系,作者对239例ADPKD及189例无ADPKD的患者家庭成员进行研究。所有上述成员均进行腹部超声检查,大部分ADP-KD病例还进行了肝酶学、血清肌酐、24小时尿肌酐检查。ADPKD诊断依据双侧肾囊肿的存在及囊肿数量≥5个。只要肝内发现囊肿则为合并肝囊性病(ADPKD+HC),未发现囊肿则认为不伴有肝囊性病(ADPKD-HC)。结果,ADPKD病人中有116例(48%)伴有肝囊肿,其年龄较ADPKD-HC病人为大(44.6±1.1岁/32.9±1.1岁,P<0.0001)。肝囊肿数量随年龄增加(P<0.
Polycystic liver disease is a common manifestation of autosomal dominant polycystic kidney disease (ADPKD). The relationship between the formation of liver cysts and renal cysts and other extrarenal manifestations has not yet been reported, in order to determine the age, gender, pregnancy, renal function, renal cystic degeneration and other renal manifestations and liver cystic disease, the author of 239 Cases of ADPKD and 189 cases of family members without ADPKD were studied. All of the above-mentioned members underwent abdominal ultrasonography, and most of ADP-KD cases were also subjected to liver enzymology, serum creatinine, and 24-hour urinary creatinine. ADPKD diagnosis based on the presence of bilateral renal cysts and the number of cysts ≥ 5. As long as the intrahepatic cyst is combined with hepatic cystic disease (ADPKD + HC), cyst is not found without hepatic cystic disease (ADPKD-HC). As a result, 116 (48%) of ADPKD patients had hepatic cysts, which were older than ADPKD-HC patients (44.6 ± 1.1 years /32.9 ± 1.1 years, P <0.0001). The number of hepatic cysts increased with age (P <0.