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絲虫病是寄生虫病危害性較为严重的一种,在我国流行的区域非常广泛,如山东、四川以及东南沿海各省均有出現,各地的感染率高达30%以上。絲虫病的治疗药物,一般公認益羣生是較好的一种。該药物虽然对幼絲虫有显著疗效,但对若干品种的成虫,如蟠尾、罗阿和鼠絲虫等都不太好;而且本化合物服后,往往引起头痛、嘔吐以及發热等副作用,因此更理想的新药,尚有待于繼續的研究。本文目的在供今后新药設計或治疗上的参考。
Filariasis is a kind of serious parasitic disease, and it is very popular in China. It has appeared in Shandong, Sichuan, and the southeastern coastal provinces, and the infection rate is as high as 30%. The treatment of filariasis is generally recognized as a better one. Although the drug has a significant effect on larvae, it is not very good for some adult worms such as iris, roe, and rat filar; and after serving the compound, it often causes side effects such as headache, vomiting, and fever. Therefore, the more ideal new drugs still need to be continued. The purpose of this article is to provide reference for future drug design or treatment.