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阿片及其制剂(阿片酊及阿片浸膏)中吗啡的含量如照英美及日本药典方法化验,每不易得正确结果。中国药典中所规定的方法係取英美药典方法之长,虽较为优良,但仍不能算为理想的方法。苏联药典测定阿片制剂中吗啡含量之方法可以参考,其前段操作与英美日各国药典同一原理,即检品与新鲜氧化钙加水研磨,加硫酸铵使吗啡析出,用苯洗去其他生物鹼後,用氯仿与酒精之混合液抽提吗啡,唯最後
The content of morphine in opioids and their preparations (opioids and opioid extracts) is tested according to the methods of the Anglo-American and Japanese Pharmacopoeia and it is not easy to obtain correct results. The method prescribed in the Chinese Pharmacopoeia is based on the length of the Anglo-American Pharmacopoeia method. Although it is relatively good, it cannot be considered an ideal method. The method used in the Soviet Pharmacopoeia to determine the content of morphine in opioids can be referred to. The previous operation is the same as the principles of the United Kingdom, the United States, and the Pharmacopoeia of the United States, that is, the sample is ground with fresh calcium oxide and water, and ammonium sulphate is added to precipitate morphine. After washing out other alkaloids with benzene, Extracting morphine with a mixture of chloroform and alcohol.