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本世纪50年代以来,学者们发现应用皮质类固醇可引起眼内压升高并导致激素性青光眼。为了探讨皮质类固醇与原发性开角型青光眼(POAG)的关系,60年代开始,以Becker和Armaly等为代表作了一系列局部皮质类固醇升压试验,至1968年Leveae等提出血浆皮质醇抑制试验,于70年代,Bigger等又提出淋巴细胞转化抑制试验。从而形成了三种类型皮质类固醇试验。在国外,对皮质类固醇试验与POAG的关系有两种不同见解;在国
Since the 1950s, scholars have found that the use of corticosteroids can cause elevated intraocular pressure and lead to steroid-induced glaucoma. In order to explore the relationship between corticosteroids and primary open-angle glaucoma (POAG), a series of topical corticosteroid-boosting tests were carried out in the 1960s, with Becker and Armaly as the representative. Until 1968, Leveae et al proposed plasma cortisol inhibition test In the 1970s, Bigger et al proposed a lymphocyte transformation inhibition test. This resulted in three types of corticosteroid tests. In foreign countries, there are two different opinions on the relationship between corticosteroid test and POAG; in the country