Ⅱ型糖尿病及其治疗、治疗药物的研究进展与临床评价

• 作 者: 马华
• 出 处: 上海医药情报研究
• 发表日期: 2001年01期
• 关键词: Ⅱ型糖尿病 磺酰脲类药物 格列奈类药物 高血糖症 甲福明 瑞格列奈 阿卡波糖 血糖控制目标 抗糖尿病药物 磺酞脉类

一、概况就在5年前,Ⅱ型糖尿病治疗的靶的尚仅为高血糖症而未包括其客观存在的一个主要病因胰岛素抗性,可用药物也只有口服磺酰脲类药物和外源性注射用胰岛素两类。更严重的是,Ⅱ型糖尿病治疗的病理目标在相当长时间内没有得到合理和科学的阐释。然今天,无论是有关Ⅱ型糖尿病控制目标、抑或其治疗药物都有了实质性的进步和发展。

First, an overview Just 5 years ago, the target of type 2 diabetes treatment is only hyperglycemia and does not include its objective existence of a major cause of insulin resistance, the available drugs are only oral sulfonylureas and exogenous Two types of insulin for injection. More seriously, the pathological target of type 2 diabetes treatment has not been reasonably and scientifically explained for a long time. Today, however, both the goal of type II diabetes control, or its treatment of drugs have made substantial progress and development.