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目的:观察对比托烷司琼和昂丹司琼对腹腔镜下子宫肌瘤挖除术患者术后止吐的效果。方法:选择择期行腹腔镜下子宫肌瘤挖除术60例,随机分为三组,诱导前10min分别给予生理盐水5ml、昂丹司琼4mg(稀释至5m1)、托烷司琼5mg(稀释至5m1),手术结束后观察患者从拔除气管导管开始的24h之内恶心与呕吐症状的发生情况。结果:生理盐水组(Ⅰ组)、昂丹司琼组(Ⅱ组)和托烷司琼组(Ⅲ组)术后24h内分别有9例、3例和4例出现恶心呕吐的症状,Ⅰ组与Ⅱ组和Ⅲ组比较,差异均具有统计学意义(P<0.05),Ⅱ组与Ⅲ组比较,差异无统计学意义(P>0.05)。结论:麻醉诱导前给予昂丹司琼和托烷司琼均可以安全有效的预防腹腔镜下子宫肌瘤挖除术后恶心呕吐的发生。
Objective: To compare the efficacy of tropisetron and ondansetron on antiemetic in patients undergoing laparoscopic myomectomy. Methods: Sixty patients undergoing laparoscopic uterine fibroids were randomly divided into three groups: normal saline 5ml, ondansetron 4mg (diluted to 5ml), tropisetron 5mg (diluted To 5m1). After the surgery, the occurrence of nausea and vomiting was observed within 24 hours after the removal of the tracheal tube. Results: Nine cases were observed in 9 hours, 3 cases and 4 cases of nausea and vomiting symptoms in group Ⅰ, group Ⅱ and group Ⅲ respectively There was significant difference between group Ⅱ and group Ⅲ (P <0.05). There was no significant difference between group Ⅱ and group Ⅲ (P> 0.05). Conclusion: Ondansetron and tropisetron can be given safely and effectively before anesthesia induction to prevent nausea and vomiting after laparoscopic myomectomy.