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目的探讨外周血WBC、CRP及血糖在手足口病重症病例早期识别中的临床应用价值。方法选取2013年1月—2015年1月收治的60例手足口病患者作为研究对象,根据病情分为普通病例组27例和重症病例组33例。检测并比较两组患儿的外周血WBC、CRP及血糖水平。计量资料采用t检验,计数资料采用χ2检验,P<0.05为差异有统计学意义。结果重症病例组的外周血WBC、CRP及血糖阳性率分别为33.3%、93.9%、87.9%,均高于普通病例组的7.4%、37.0%、29.6%,差异均有统计学意义(均P<0.05)。重症病例组外周血WBC、CRP及血糖水平分别为(10.46±3.52)×109/L、(6.83±3.95)mg/L、(9.85±3.04)mmol/L,均高于普通病例组的(7.16±2.34)×109/L、(3.07±2.28)mg/L、(6.37±1.32)mmol/L,差异均有统计学意义(均P<0.05)。结论外周血WBC、CRP及血糖的检查是早期诊断重症手足口患儿的有效方法,在临床诊断重症手足口病患儿中具有较高的诊断价值。
Objective To investigate the clinical value of peripheral blood WBC, CRP and blood glucose in the early identification of severe cases of hand-foot-mouth disease. Methods Sixty HFMD patients admitted from January 2013 to January 2015 were selected as the study subjects. According to the disease, 27 cases were divided into general cases and 33 cases with severe cases. The levels of WBC, CRP and blood glucose in peripheral blood of the two groups were detected and compared. Measurement data using t test, count data using χ2 test, P <0.05 for the difference was statistically significant. Results The WBC, CRP and the positive rate of blood glucose in severe cases were 33.3%, 93.9% and 87.9%, respectively, which were higher than those in common cases (7.4%, 37.0% and 29.6%, respectively) <0.05). The levels of WBC, CRP and blood glucose in severe cases were (10.46 ± 3.52) × 109 / L, (6.83 ± 3.95) mg / L and (9.85 ± 3.04) mmol / L, ± 2.34) × 109 / L, (3.07 ± 2.28) mg / L and (6.37 ± 1.32) mmol / L, respectively (all P <0.05). Conclusion The detection of peripheral blood WBC, CRP and blood glucose is an effective method for the early diagnosis of severe hand-foot-mouth disease in children with severe hand-foot-mouth disease, which has high diagnostic value.