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目的探讨喉次全切除治疗喉癌的临床疗效观察。方法分析2011年6月至2013年6月我院耳鼻喉外科收治的98例行喉次全切除术的喉癌患者,按国际抗癌协会(UICC)2002年标准分级、分期:T1N1M0有23例,T2N0M0有18例,T3N0M0有25例,T3N1M0有21例,T3N2M0有11例,分别给予喉次全切除治疗,观察治疗效果。结果 98例患者中有88例术后效果满意,不影响发声交谈功能;其余10例中有5例出现发声管狭窄而用力呼吸气形成高压语音,3例经CT复查证实发生发声管闭锁,2例患者局部复发死亡。1、3、5年生存率分别为65.3%、56.6%、41.9%。结论行环状软骨上喉次全切除术治疗喉癌是一种操作简单的有效术式,可以达到保留喉癌患者的发声功能和提高患者的生存率及生存质量。
Objective To investigate the clinical effects of total subtotal laryngectomy in the treatment of laryngeal cancer. Methods A total of 98 patients undergoing laryngectomy for total laryngectomy undergoing total laryngectomy were enrolled in our department from June 2011 to June 2013. According to the 2002 UICC criteria, the patients were divided into three groups: T1N1M0 with 23 cases There were 18 cases of T2N0M0, 25 cases of T3N0M0, 21 cases of T3N1M0 and 11 cases of T3N2M0. All patients underwent total laryngectomy, and the therapeutic effect was observed. Results Of the 98 patients, 88 patients were satisfied with the results after operation, and did not affect vocalization. In the remaining 10 patients, stenosis was found in 5 patients and high-pressure voice was made in forced breathing. Three patients were confirmed by CT scan. Patients with local recurrence of death. The 1, 3, 5 year survival rates were 65.3%, 56.6% and 41.9% respectively. Conclusions Circumcisional cartilage laryngectomy for the treatment of laryngeal cancer is a simple and effective procedure, which can preserve the vocal function of patients with laryngeal cancer and improve the survival rate and quality of life of patients.