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又名:A-938u;BW-A938u;奴罗马科斯。化学名为1,2,3,4-四氢-2-(3-羟基丙基)-6,7,8-三甲氧基-2-甲基-1-(3,4,5三甲氧基苄基)异喹啉氯化物,琥珀酸盐(2:1),[CAS-83348-52-1和106819-53-8].本品是(1R,1’S,2S,2’R)、(1R,1’R,2S,2’S)和(1S,1’S,2R,2’R)的混合物,为双苄基异喹啉二酯的异构体,对神经肌肉具有持久的阻断作用。本品是由威尔康公司研制开发的。早在1989年美国新药应用部门就曾向该公司提出以2500万美元作为技术转让费的要求。在英国正在对其进行Ⅲ期临床试验,并准备申请注册。以卤代烷麻醉过的儿童,用本品0.03mg/kg时不产生副作用,用于具有长时期作用的插管法也可
Also known as: A-938u; BW-A938u; slave Marcos. Chemically named 1,2,3,4-tetrahydro-2- (3-hydroxypropyl) -6,7,8-trimethoxy-2-methyl-1- (3,4,5trimethoxy Benzyl) isoquinoline chloride, succinate (2: 1), [CAS-83348-52-1 and 106819-53-8] This product is (1R, 1’S, 2S, 2’R), 1R, 1’R, 2S, 2’S) and (1S, 1’S, 2R, 2’R) is an isomer of bisbenzyl isoquinoline diester with a permanent block on neuromuscular blockade. This product is developed by the Wellcome company. As early as 1989, the New Drug Application Division of the United States proposed to the company a request of 25 million U.S. dollars as technology transfer fee. It is undergoing Phase III clinical trials in the UK and is ready to apply for registration. To halogenated anesthesia in children, with this product 0.03mg / kg does not produce side effects for intubation with long-term effect can also be