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目的:观察痰热清注射液辅助治疗毛细支气管炎的疗效。方法:将120例毛细支气管炎患儿随机分为两组,观察组62例,对照组58例。两组均给予抗感染、氨茶碱、酚妥拉明、吸氧、退热、化痰、平喘等对症支持综合处理,并保持呼吸道通畅,纠正水、电解质及酸碱平衡,若患儿合并呼吸衰竭、心力衰竭等严重的并发症,给予利尿、血管活性药、强心等对应的抢救。观察组在上述治疗基础上加用痰热清注射液0.8mL.kg-1.24h-1加入5%葡萄糖注射液100mL,静脉点滴,每天1次。两组均以7天为1个疗程,超过3个疗程即终止对照观察。结果:观察组总有效率明显优于对照组,两组比较有显著性差异(P<0.05),两组在退热、化痰止咳、解痉平喘、肺部干湿性罗音消失方面,观察组治疗所需时间明显短于对照组,经统计分析有非常显著性差异(P<0.01),观察组的住院天数及心力衰竭与呼吸衰竭纠正所需时间明显短于对照组,经统计学分析有显著性差异(P<0.05)。结论:痰热清注射液治疗毛细支气管炎疗效令人满意,值得临床推广。
Objective: To observe the effect of Tanreqing injection in the treatment of bronchiolitis. Methods: 120 cases of bronchiolitis were randomly divided into two groups, observation group 62 cases, control group 58 cases. Both groups were given anti-infection, aminophylline, phentolamine, oxygen, antipyretic, phlegm, asthma and other symptomatic support comprehensive treatment, and to maintain airway patency, correct water, electrolyte and acid-base balance, if children Merger respiratory failure, heart failure and other serious complications, giving diuretic, vasoactive drugs, such as cardiac rescue corresponding. The observation group was added with Tanreqing Injection 0.8mL.kg-1.24h-1 on the basis of the above treatment and 100mL of 5% glucose injection was intravenously dripped once daily. Both groups were 7 days for a course of treatment, more than 3 courses to terminate the control observation. Results: The total effective rate of the observation group was significantly better than that of the control group, there was significant difference between the two groups (P <0.05). The two groups were observed in the aspects of fever, phlegm and relieving cough, antispasmodic and asthma, The time required for treatment was significantly shorter than that of the control group (P <0.01). The length of stay in hospital and the time needed to correct heart failure and respiratory failure in the observation group were significantly shorter than those in the control group. After statistical analysis There was significant difference (P <0.05). Conclusion: Tanreqing injection for the treatment of bronchiolitis is satisfactory, worthy of clinical promotion.