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有规律月经和排卵、输卵管通畅、其丈夫精液有生育力、性交后试验阳性的妇女的不育,按 BO_3 分类属于原因不明的不育。本型不育占女性不育8～10%。理论上,免疫学因素能影响生殖过程每一阶段,可在本型不育病人的生殖功能障碍中起一定作用。已知,配子、受精卵和发育早期胚胎是所有同成熟机体一样的非特异性抗原的携带者。从不育妇女的血液和生殖道内检出抗精子、抗卵巢组织、抗透明带的抗体,证实了免疫学因素在受胎和新机体发育过程中的作用。排卵期和卵子植入期 T 细胞活性抑制也说明了这一点。因此,在一定程度上,生殖过程个别环节取决于免疫系统状态及其对抗原因素的应答反应。但文献中尚无有关原因不明不育
Regular menstruation and ovulation, fallopian tube patency, fertility of her husband’s sperm, sex test after the test positive women infertility, according to BO_3 classification is unexplained infertility. This type of infertility accounting for female infertility 8 to 10%. In theory, immunological factors can affect each stage of the reproductive process, reproductive dysfunction in this type of infertility patients play a role. It is known that gametes, fertilized eggs and early developing embryos are carriers of all nonspecific antigens that are identical to mature organisms. Anti-sperm, anti-ovarian tissue and anti-zona pellucida antibodies were detected from the blood and genital tract of infertile women, confirming the role of immunological factors in the development of the fetus and new body. Ovulation and egg implantation T cell activity inhibition also illustrates this point. Thus, to some extent, individual aspects of the reproductive process depend on the state of the immune system and its response to antigenic factors. However, there is no unexplained infertility in the literature