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目的观察米非司酮联合乳酸依沙吖啶在有剖宫产史中期妊娠引产的临床效果。方法收集我院66例有剖宫产史妊娠14～26周引产孕妇,分为两组。观察组34例为米非司酮联合乳酸依沙吖啶引产,对照组单用乳酸依沙吖啶引产。观察两组阵痛出现时间、胎儿及胎盘娩出情况、产时产后失血量、软产道损伤及引产成功率。结果观察组宫缩发动时间早,产程短,胎盘胎膜剥离完整率高,产后出血量少,软产道损伤小,引产成功率100%,与对照组比较,差异有统计学意义(P<0.01)。结论米非司酮联合乳酸依沙吖啶用于有剖宫产史中期妊娠引产,具有临床效果显著,方法安全,缩短产程,减少产时产后出血量,减少软产道损伤的优点,提高了引产成功率。
Objective To observe the clinical efficacy of mifepristone combined with ethacridine lactate in induction of labor during the second trimester of pregnancy with cesarean section. Methods 66 pregnant women with history of cesarean section were enrolled in this study. Pregnant women of induced abortion were divided into two groups. The observation group 34 cases of mifepristone combined with lactic acid ethacridine induction of labor, the control group alone with lactic acid ethacridine induction. The onset of labor, the delivery of fetus and placenta, the amount of postpartum blood loss, the injury of soft birth canal and the success rate of induction of labor were observed. Results Compared with the control group, the observation group had earlier onset of contractions, shorter duration of labor, higher intact rate of placental membranes, less postpartum hemorrhage, less injury of soft birth canal, and 100% induction of labor. The difference was statistically significant (P <0.01) ). Conclusions Mifepristone combined with ethacridine lactate is suitable for induction of labor during the second trimester of pregnancy with cesarean section. It has the advantages of clinical efficacy, safety, shortening of labor, reducing postpartum hemorrhage and reducing injury of soft birth canal, Success rate.