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通过化学诱导法建立大鼠口腔癌模型,采用银染核仁组织区法对7例正常黏膜和63例不同癌变发展阶段黏膜细胞的增殖状态进行检测。结果:随着异常增生程度和组织病理学分级的增加,AgNOR颗粒计数逐渐增多。单纯性增生、异
The model of oral cancer in rats was established by chemical induction method. The proliferative state of 7 normal mucosa and 63 mucosal cells in different stages of carcinogenesis was detected by silver staining and nuclear zone method. Results: With the increase of the degree of abnormal proliferation and the histopathological grade, the AgNOR particle counts gradually increased. Simple hyperplasia, different