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心得安可抑制人精子活力。最近Zipper等评价了心得安作为阴道避孕药的可能性,但它对生殖直接作用方式和对获能的影响尚未见报道。本文研究了DL-心得安(DL-P)对豚鼠体外精子活动和获能的影响。 豚鼠精子采用体外培养。培养基系改良的Barros无钙最小获能培养基(MCM)。精子取自成熟豚鼠输精管及附睾尾,精子数调至10~7 Cells/ml。实验在37℃进行。(1)观察DL-P对精子活力的抑制作用,精子在含不同浓度DL-P(0.1～
Encore inhibits human sperm motility. Zipper et al. Recently evaluated propranolol as a vaginal pill, but its direct effect on reproduction and its effects on empowerment have not been reported. This article investigates the effects of DL-P on sperm motility and capacitation in guinea pigs. Guinea pig sperm were cultured in vitro. Cultured Barros Calcium-Free Minimal Efficient Media (MCM). Sperm from mature guinea pig vas deferens and epididymal tail, sperm number adjusted to 10 ~ 7 Cells / ml. Experiments were performed at 37 ° C. (1) To observe the inhibitory effect of DL-P on sperm motility, sperm in different concentrations of DL-P (0.1 ~