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本文报告了20例正常对照和30例肝病患者(原发性肝癌10例、慢性肝炎15例、肝硬化5例)的99mTc-NGA肝受体显你的结果。作者设计了一套肝受体显像综合诊断方案,包括系列动态摄取图象、药代动力学参数、HEF、T90和T90参数显象,以定性评价肝受体的浓度和空间分布,定量评价肝功能方向性变化,定量评价总体肝功能(包括摄取量和摄取速度)和定量批价局部(每像素单元)肝功能。资料表明,该方法对肝占位性病变的诊断、功能栓肝细胞数量的估计和肝贮备功能的评价都有较大价值。
This paper reports the results of 99mTc-NGA hepatic receptors in 20 normal controls and 30 patients with liver disease (10 with primary liver cancer, 15 with chronic hepatitis and 5 with cirrhosis). The authors designed a comprehensive diagnostic program for liver receptor imaging including a series of dynamic uptake images, pharmacokinetic parameters, HEF, T90 and T90 parameter imaging to qualitatively assess the concentration and spatial distribution of liver receptors, and quantitatively evaluate Changes in the direction of liver function, quantitative assessment of overall liver function (including intake and speed of intake) and quantitatively approved local (per pixel unit) liver function. The data show that the method of liver space-occupying lesions diagnosis, functional assessment of the number of liver cells and hepatic reserve function evaluation have great value.