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1．前言胶质细胞株源性神经营养因子（Glialcellline－derivedneurotrophicfactor，GDNF）是多种神经元存活的必需因子。最初是由小鼠胶质细胞株B49细胞分离的精基化的二硫键结合的二体蛋白质，有134个氨基酸。它的7个半胱氨酸残基依其在分子中的配布位置与转化生长因子-β（tr
1. Preface Glial cell line-derived neurotrophic factor (GDNF) is an essential factor for the survival of a variety of neurons. It was originally a finely-divided disulfide-bonded dimeric protein isolated from the mouse glioblastoma B49 cells with 134 amino acids. Its seven cysteine residues according to their distribution in the molecule position and transforming growth factor-β (tr