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目的:分析保定地区人乳头瘤病毒(HPV)感染情况及亚型分布规律。方法:以2010年2月～2011年3月在保定市妇幼保健院就诊的有宫颈病变的462例女性患者为研究对象进行HPV-DNA分型检测,采集其阴道宫颈分泌物标本进行21种HPV基因型的分型检测,分析常见感染亚型及分布规律。结果:HPV总阳性率为50.22%,常见的高危型为HPV16、HPV58和HPV52,低危型为HPV6和HPV11。结论:保定地区HPV感染率较高,常见感染亚型符合亚洲人群的分布规律,同时又有一定的区域性。
Objective: To analyze the human papillomavirus (HPV) infection and subtype distribution in Baoding area. Methods: A total of 462 female patients with cervical lesions who were treated in MCH from February 2010 to March 2011 were tested for HPV-DNA typing. The samples of vaginal cervical secretions were collected for 21 types of HPV Genotyping detection, analysis of common subtypes of infection and distribution. Results: The total positive rate of HPV was 50.22%. The common high-risk types were HPV16, HPV58 and HPV52, and the low-risk types were HPV6 and HPV11. Conclusion: The prevalence of HPV infection in Baoding area is high, and the common subtypes of infection are in accordance with the distribution rules of Asian population. At the same time, there are certain regionalities.