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目的:分析总结老年糖尿病慢性并发症发病时间与危险因素。方法:选取120例2016年1月至2017年1月我院收治的糖尿病足患者,根据有无坏疽分为坏疽组(50例)和非坏疽组(70例),回顾分析两组患者的临床资料,并对其一般资料、病史以及实验室检查结果进行比较。结果:坏疽组与非坏疽组的年龄、性别、BMI、病史、血糖、血压、血脂、HbAlc、BUN、Scr等指标比较,差异不明显(P>0.05)。两组WBC、ABI、ALB以及CRP水平比较,具有统计学意义(P<0.05)。多因素回归分析显示ABI、WBC、ALB和CRP都是糖尿病足坏疽的独立危险因素。结论:糖尿病足坏疽的发生与WBC和CRP水平升高、ALB和ABI降低具有较大关系,临床应有针对性的进行防治。
Objective: To analyze the time and risk factors of chronic complications of senile diabetes. Methods: 120 patients with diabetic foot admitted to our hospital from January 2016 to January 2017 were divided into gangrenous group (n = 50) and non-gangrene group (n = 70) according to their presence or absence of gangrene. The clinical data of two groups were retrospectively analyzed Data, and its general information, medical history and laboratory test results were compared. Results: There was no significant difference in age, sex, BMI, history, blood glucose, blood pressure, blood lipid, HbAlc, BUN and Scr between gangrenous and non-gangrene groups (P> 0.05). The levels of WBC, ABI, ALB and CRP in the two groups were statistically significant (P <0.05). Multivariate regression analysis showed that ABI, WBC, ALB and CRP were all independent risk factors for diabetic foot gangrene. Conclusion: The incidence of diabetic foot gangrene is associated with an increase in the levels of WBC and CRP, a decrease in ALB and ABI, and clinical prevention and treatment should be targeted.