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近年来多能干细胞引起了许多科学家的关注 ,在临床中已被作为一种基因治疗和细胞治疗手段广泛应用于多种难治之症的研究 ,如帕金森病、老年性痴呆、肿瘤以及器官移植等。同时 ,多能干细胞作为一种原始细胞具有旺盛的增殖、自我稳定能力和多向分化的潜能 ,因此 ,还可以作为一种新的测试细胞应用于环境因素致发育毒性的检测和机制研究。它的应用无疑为生殖发育毒理研究打开了一扇崭新的大门。
In recent years, pluripotent stem cells have attracted the attention of many scientists and have been widely used clinically as a kind of gene therapy and cell therapy for many refractory diseases such as Parkinson’s disease, Alzheimer’s disease, cancer and organ transplantation Wait. Meanwhile, as a primitive cell, pluripotent stem cells have the potential of proliferation, self-stabilization and multidirectional differentiation. Therefore, they can also be used as a new test cell for the detection and mechanism research of developmental toxicity caused by environmental factors. Its application undoubtedly opens up a whole new door to the study of reproductive and developmental toxicology.