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目的分析消化科住院患者医院感染的病原菌分布及耐药性,为临床有效的经验性用药提供参考依据。方法选择2014年3月-2015年3月于医院消化科就诊的880例患者,分析患者感染病原菌的分布及药敏试验结果,数据采用SPSS 13.0软件进行统计分析。结果感染患者共96例,感染率为10.91%;以消化系统感染为主,共35例占36.46%;96例感染患者共检出121株病原菌,以革兰阴性菌为主,共72株占59.51%;革兰阴性菌主要为大肠埃希菌、肺炎克雷伯菌,分别占24.79%、11.57%;大肠埃希菌对头孢哌酮/舒巴坦、亚胺培南及头孢哌酮/舒巴坦较敏感,敏感率均>70.00%,肠球菌属、金黄色葡萄球菌对万古霉素较敏感,敏感率均>79.00%。结论消化科住院患者相对感染率低,以消化系统感染为主,常见病原菌为革兰阴性菌,经验性用药可以考虑碳青霉烯类抗菌药物。
Objective To analyze the distribution and drug resistance of pathogenic bacteria in Nosocomial Infectious Diseases in Inpatients of Gastroenterology, and to provide a reference for clinical and empirical empirical drug use. Methods From March 2014 to March 2015, 880 patients admitted to the Department of Gastroenterology of the Hospital were selected to analyze the distribution of pathogens and drug susceptibility test results. The data were analyzed by SPSS 13.0 software. Results A total of 96 patients were infected, the infection rate was 10.91%; mainly digestive system infection, a total of 35 cases accounted for 36.46%; 121 strains of pathogens were detected in 96 patients infected with Gram-negative bacteria, a total of 72 strains 59.51% respectively. Gram-negative bacteria were mainly Escherichia coli and Klebsiella pneumoniae, accounting for 24.79% and 11.57%, respectively. Escherichia coli was sensitive to cefoperazone / sulbactam, imipenem and cefoperazone / Sulbactam was more sensitive, the sensitivity rate was> 70.00%, Enterococcus, Staphylococcus aureus were more sensitive to vancomycin, the sensitivity rates were> 79.00%. Conclusions The relative infection rate of inpatients with gastroenterology is low, with digestive system infection as the main pathogen. Gram-negative bacteria are the common pathogens, and carbapenem-based antibiotics can be considered empirically.