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目的观察异常体液型OLP病损组织中T细胞表达和分泌的活性调节蛋白(RANTES)含量的变化,探讨RANTES在OLP维吾尔医学异常体液分型中的临床意义。方法对本院门诊就诊的76例OLP患者进行异常体液分型分组,采用免疫组化SP法检测OLP组织中RANTES的表达水平。结果 OLP患者中异常血液质51例(67.11%)、异常胆液质6例(7.89%)、异常黏液质15例(19.74%)、异常黑胆质4例(5.26%);RANTES在不同体液质型的表达为异常血液质52.63%、异常胆液质7.89%、异常黏液质14.47%,异常黑胆质中不表达。结论异常血液质与OLP的发生发展可能存在一定关系,RANTES可能可以作为异常血液质OLP的靶向指标。
Objective To observe the changes of T cell expression and secretion of RANTES in abnormal body fluid OLP lesions and to investigate the clinical significance of RANTES in OLP Uyghur medical abnormalities. Methods Sixty-six patients with OLP diagnosed as outpatients in this hospital were divided into two groups according to their body fluids. The expression of RANTES in OLP tissues was detected by immunohistochemical SP method. Results There were 51 cases (67.11%) of abnormal blood clot in OLP, 6 cases (7.89%) of abnormal bile duct, 15 cases (19.74%) of abnormal myxoid and 4 cases of abnormal savda (5.26% The expression of the type of abnormal blood was 52.63%, 7.89% of abnormal bilirubin, abnormal mucin 14.47%, abnormal savda not expressed. Conclusions Abnormal blood quality may be related to the occurrence and development of OLP. RANTES may be used as a target of OLP in abnormal blood.