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目的探讨醒脑对急性脑出血所诱发的全身炎症反应综合征(SIRS)的作用及可能机制。方法选择出血量在5～30毫升急性脑出血患者80名,随机分成治疗组及对照组,每组各40名。根据SIRS的诊断标准,观察各组出现SIRS的例数及反应的程度,进行比较。结果治疗组出现SIRS 15例,发生率37.5%;对照组27例,发生率67.5%。两组比较差异显著(P<0.01)。结论醒脑可减少急性脑出血所诱发的全身炎症反应综合征的发生率。
Objective To investigate the effect and possible mechanism of resuscitation on systemic inflammatory response syndrome (SIRS) induced by acute intracerebral hemorrhage. Methods Eighty patients with acute cerebral hemorrhage of 5 ~ 30 ml were randomly divided into treatment group and control group, 40 in each group. According to the diagnostic criteria of SIRS, the incidence of SIRS in each group was observed and compared. Results 15 cases of SIRS occurred in the treatment group, the incidence rate was 37.5%. In the control group, 27 cases were found, the incidence rate was 67.5%. The difference between the two groups was significant (P <0.01). Conclusion Xingnao can reduce the incidence of systemic inflammatory response syndrome induced by acute cerebral hemorrhage.