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目的 探讨慢性重型肝炎和肝硬化并发自发性细菌性腹膜炎 (SBP)菌株种类、临床特点和预后。方法 对 16 8例住院慢性重型肝炎和肝硬化并发SBP临床资料进行回顾性分析。结果 14 2例 (85 71% )患者多核细胞 (PMN)相对值≥ 0 5 0。 32例腹水细菌培养阳性 ,共分离细菌 4 2株 ,大肠埃希菌占 4 2 % ,腹水蛋白≤ 10g/L并发SBP发生率高于腹水蛋白 >10g/L患者。两者差异显著 (P <0 0 5 )。结论 慢性重型肝炎和肝硬化并发SBP临床症状大多不典型 ,腹水PMN比值是诊断SBP比较可靠的参数。病原菌以大肠杆菌为主。腹水蛋白 <10g患者应警惕SBP发生 ,应及早做腹水常规检查
Objective To investigate the types, clinical features and prognosis of spontaneous bacterial peritonitis (SBP) in patients with chronic severe hepatitis and cirrhosis. Methods The clinical data of 168 patients with chronic severe hepatitis and cirrhosis complicated with SBP were retrospectively analyzed. Results The relative value of multinucleated cells (PMN) in 14 2 patients (85 71%) was ≥ 0 50. 32 cases of ascites bacterial culture were positive, 42 strains of bacteria were isolated, Escherichia coli 42%, ascites protein ≤ 10g / L concurrent SBP higher than the incidence of ascites protein> 10g / L patients. The difference was significant (P <0 05). Conclusion Most clinical symptoms of chronic severe hepatitis and cirrhosis complicated with SBP are not typical. Ascites PMN ratio is a reliable parameter to diagnose SBP. Escherichia coli-based pathogens. Ascites protein <10g patients should be alert SBP occurred, routine ascites routine examination should be done as soon as possible