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目的探讨影响足月儿发生呼吸窘迫综合征(RDS)的危险因素。方法选择本院RDS足月儿为病例组,同期住院健康足月儿为健康对照组。对2组儿童出生体质量、胎龄、性别、分娩方式、是否多胎、是否有产时窒息和宫内窘迫、母亲是否有糖尿病、是否有脐带绕颈因素进行单因素方差分析和多因素Logistic回归分析。结果单因素方差分析结果显示,影响足月儿发生RDS的因素包括男童、剖宫产、出生体质量、母亲有糖尿病、宫内窘迫、产时窒息、脐带绕颈。多因素非条件Logistic回归分析结果提示男童、剖宫产、出生体质量、母亲有糖尿病、宫内窘迫与足月儿RDS的发生密切相关。结论男童、剖宫产、母亲有糖尿病、宫内窘迫是足月儿发生RDS的危险因素,而高出生体质量是足月儿发生RDS的保护因素。
Objective To investigate the risk factors of respiratory distress syndrome (RDS) in term infants. Methods RDS full-term children in our hospital were selected as case group and full-term hospitalized healthy children as healthy control group. Two groups of children birth weight, gestational age, gender, mode of delivery, whether or not multiple births, whether there is labor-induced asphyxia and intrauterine distress, whether the mother has diabetes, whether there is umbilical cord around the neck factor analysis of variance and multivariate Logistic regression analysis. Results The results of one-way ANOVA showed that the factors affecting RDS of full-term infants included boy, cesarean section, birth weight, mother with diabetes, intrauterine distress, asphyxia during labor and umbilical cord around the neck. Multivariate non-conditional logistic regression analysis showed that boys, cesarean section, birth weight, maternal diabetes, intrauterine distress were closely related to the occurrence of RDS in term infants. Conclusions Boys, cesarean section, mothers with diabetes mellitus, intrauterine distress are risk factors for RDS in term infants, and high birth weight is the protective factor of RDS in term infants.