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目的:评价尿激酶对急性ST段抬高型心肌梗死患者溶栓疗效的影响。方法:选取医院2015年5月—2016年7月期间收治的急性ST段抬高型心肌梗死患者72例临床资料,将其随机分为观察组与对照组(每组36例);对照组患者给予皮下注射低分子肝素钠治疗,观察组患者给予尿激酶静脉溶栓治疗,比较两组患者用药后的总有效率以及再通率和并发症的发生率。结果:观察组患者用药后6 h内再通率、总再通率均高于对照组(P<0.05),并发症的发生率低于对照组(P<0.05),治疗的总有效率高于对照组(P<0.05)。结论:采用尿激酶静脉注射治疗急性ST段抬高型心肌梗死患者溶栓疗效优于低分子肝素钠,能有效提高用药后6 h内的再通率,并发症的发生率较低。
Objective: To evaluate the effect of urokinase on thrombolysis in patients with acute ST-segment elevation myocardial infarction. Methods: The clinical data of 72 patients with acute ST-segment elevation myocardial infarction admitted from May 2015 to July 2016 in our hospital were selected and randomly divided into observation group and control group (36 in each group). Patients in the control group Subcutaneous injection of low molecular weight heparin sodium was given to patients in the observation group. Patients in the observation group were given intravenous thrombolysis with urokinase. The total effective rate, recanalization rate and complication rate were compared between the two groups. Results: The recanalization rate and total recanalization rate within 6 hours after treatment in the observation group were significantly higher than those in the control group (P <0.05), and the incidence of complications was lower than that in the control group (P <0.05). The total effective rate of treatment was high In the control group (P <0.05). Conclusion: The intravenous injection of urokinase in patients with acute ST-segment elevation myocardial infarction is superior to low-molecular-weight heparin in thrombolysis, which can effectively improve the recanalization rate within 6 h after treatment, and the incidence of complications is low.