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目的 分析胃黏膜活检中黏液细胞癌的病变特点 ,总结其临床病理特征 ,避免误诊漏诊。方法 通过组织病理学和组织化学PAS、AB染色法 ,对 93例胃黏液细胞癌黏膜活检标本进行病理观察。结果 根据组织学特点 ,将癌组织分布形式分为黏膜固有层浅层、黏膜固有层深层、弥漫分布、黏膜边缘及坏死组织周围 5种病变类型 ,其在 93例标本中分别占 8 6 %、31 2 %、30 1%、11 8%和 18 3%。每种黏液细胞癌类型的细胞形态、排列方式及细胞周围的组织变化均有所不同 ,其癌细胞也具有不同的形态特征和黏液分泌特点。结论 胃黏液细胞癌的形态特征与组织分布具有相对的特殊性 ,掌握其特点可以在外科病理检查中减少误诊漏诊
Objective To analyze the characteristics of mucous cell carcinoma in gastric mucosal biopsy and summarize its clinicopathological features to avoid misdiagnosis and missed diagnosis. Methods The histopathological and histochemical methods of PAS and AB staining were used to detect the pathological changes of mucosal biopsy specimens from 93 gastric mucosal carcinomas. Results According to the characteristics of histology, the distribution of cancer tissue was divided into superficial layers of mucosa lamina propria, deep layers of mucosa lamina propria, diffuse distribution, mucosal margins and necrotic tissue around the five types of lesions, accounting for 86% of 93 cases, 31 2%, 30 1%, 11 8% and 18 3%. Each mucinous cell carcinoma type of cell morphology, arrangement and changes in the surrounding tissue are different, the cancer cells also have different morphological characteristics and mucus secretion characteristics. Conclusion The morphological characteristics and tissue distribution of gastric mucinous cell carcinoma are relatively specific. Grasping the characteristics of gastric mucinous cell carcinoma can reduce the misdiagnosis and missed diagnosis in surgical pathological examination