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胰腺癌在全球范围内发病率和死亡率逐年增高,但防治效果仍不理想。手术切除是胰腺癌的主要治疗方式,但胰腺癌手术利弊分明。如何规避手术的弊,同时把利发挥到极致,使患者获益最大化应该是判断胰腺癌手术成功与否的主要标准。要实现胰腺癌手术的成功,围手术期必须关注肿瘤、宿主和团队的综合因素,尤其要充分认识TNM分期的局限性和重视规范化多学科诊疗模式(MDT)指导下的个体化综合诊治方案,以患者获得长期生存为终极目标,做一名合格的肿瘤外科医生。“,”The incidence and mortality of pancreatic cancer are increasing year by year worldwide, but the prevention and treatment effect is far from satisfactory. Surgical resection remains the main treatment for pancreatic cancer, but the advantages and disadvantages of surgery are clear. How to avoid the disadvantages and maximize the advantages of surgery to optimize the benefits of patients contributes the main criteria for judging whether the operation for pancreatic cancer is successful or not. In order to achieve the success of pancreatic cancer surgery, perioperative attention must be paid to the comprehensive factors including tumor, host and surgical team, especially to fully understand the limitation of TNM staging,and to emphasize the individualized comprehensive diagnosis and treatment protocol under the guidance of standardized multidisciplinary team (MDT) mode, with long-term survival as the ultimate goal of being a qualified surgical oncologist.