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Keating等在1970年首次报告2例胰腺囊性纤维性变的婴儿,有前囟隆起、吸收障碍、维生素A低下,并有贫血,淡漠、角膜溃疡。第1例血清维生素A7微克％(正常值为30～45微克％),因进行性肺炎而死亡。第2例血清胡萝卜素12微克％(正常值为50～200微克％),应用维生素治疗后前囟压力减退,其它症状迅速消失,血清胡萝卜素恢复到正常。认为颅内压增高的机制是维生素A缺乏所导致的吸收不良,并认为颅内压增高可先于其它已知症状的前几周出现。本文报告一例首先出现前囟隆起,其后证
Keating et al. First reported 2 cases of pancreatic cystic fibrosis in 1970, with anterior fontanel, disordered absorption, low vitamin A, and anemia, apathy and corneal ulcer. The first case of serum vitamin A7 micrograms% (normal 30 to 45 micrograms%), died of progressive pneumonia. The second case of serum carotene 12 micrograms% (normal value of 50 to 200 micrograms%), the application of vitamin treatment of anterior fontanelle decreased, the other symptoms disappear rapidly, serum carotene returned to normal. It is believed that the mechanism of increased intracranial pressure is malabsorption caused by vitamin A deficiency and that increased intracranial pressure may occur prior to the first few weeks of other known symptoms. This article reports a case of first appeared before the fontanel uplift, its card