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急性铜中毒已有一些报告,印度较多。儿童外源性铜中毒常由于;水源的污染,用结晶硫酸铜治疗烧伤,以及意外的服用。内源性钢中毒, ??对肝豆状核变性的病理生理起一定作用。急性铜中毒的临床表现包括:严重的胃肠刺激症状、溶血性贫血、尿少、休克,有些病例死亡。治疗方法也不外口服碘化钾、皮质类固醇、二巯基丙醇(BAL)和青霉胺。本文报告1例18个月的男孩,喝了含3克硫酸铜的溶液,1小时后入院。入院前有呕吐。入院时检查:患儿稍嗜睡,口腔粘膜染成蓝色,衣服上有淡蓝色呕吐物。病人的生命体征、血红蛋白(14.6克%)及尿液分析均正常。用牛奶(刺激缓冲剂)洗胃,直至抽出物没有蓝色。唯血清铜高达1,650微克%,正常幼儿血清铜110～170微克%,超过540微克%时可对机体产生毒性作用。数小时后逐渐迟钝,对深部疼痛有反应,呼吸和心血管系统尚无显著异常。于服铜5
There have been some reports of acute copper poisoning, more in India. Children often due to exogenous copper poisoning; water pollution, treatment with crystalline copper sulfate burns, and accidental use. Endogenous steel poisoning, liver enzymes play a role in the pathophysiology of Wilson’s disease. Clinical manifestations of acute copper poisoning include: severe gastrointestinal irritation, hemolytic anemia, oliguria, shock, and death in some cases. Treatment is no more than oral potassium iodide, corticosteroids, dimercaptopropanol (BAL) and penicillamine. This article reports an 18-month-old boy who drank a solution containing 3 grams of copper sulfate and was admitted to hospital after 1 hour. Vomiting before admission. Admission examination: children with drowsiness, oral mucosa stained blue, light blue vomit on clothes. The patient’s vital signs, hemoglobin (14.6 g%) and urine analysis were normal. Rinse the stomach with milk (stimulating buffer) until the extract is blue-colored. Only serum copper up to 1,650 micrograms%, normal child serum copper 110 ~ 170 micrograms%, more than 540 micrograms% can produce toxic effects on the body. After a few hours gradually dull, deep pain response, respiratory and cardiovascular system no significant abnormalities. In service copper 5