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β受体阻滞剂和钙通道阻滞剂在静息时有等效的降压作用已被证实,但运动时其作用尚无报道.本文在随机双盲下测定静息和运动时血压及最大?O_2,比较普萘洛尔和地尔硫(艹卓)的降压作用.方法:(1)病例选择:23例,男性,55±5岁,除1例外,均习惯久坐.仰卧舒张压在95~110mmHg,二次检查差异小于7mmHg.(2)给药方法:分三期两组,即:基础稳定期、剂量调整期(普萘洛尔组由80mg bid,隔两周加至每日480mg;
β blockers and calcium channel blockers at rest have equivalent antihypertensive effect has been confirmed, but its role in exercise has not been reported.This article in a randomized double-blind determination of resting and exercise blood pressure and O_2, to compare the antihypertensive effect of propranolol and diltiazem.Methods: (1) Case selection: 23 cases, male, 55 ± 5 years old, except for 1 case, were sedentary. Diastolic blood pressure in the 95 ~ 110mmHg, the second check the difference is less than 7mmHg. (2) administration: divided into two groups, namely: the basic stability period, dose adjustment period (propranolol group 80mg bid, every two weeks plus To 480mg daily