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可生物降解聚合物以其良好的生物相容性及自身的功能特性而受到广泛关注。经戊二醛(GA)交联的聚L-赖氨酸(PLL)水凝胶,可被蛋白酶所水解,且可选择吸附苯甲酸和酸性氨基酸等阴离子药物,因此可作为阴离子药物在体内的控释载体。聚D-赖氨酸(PDL)-甲氨蝶呤(MTX)复合物无抗肿瘤?..
Biodegradable polymers have attracted much attention due to their good biocompatibility and their own functional properties. Poly-L-lysine (PLL) hydrogels crosslinked by glutaraldehyde (GA) can be hydrolyzed by proteases and can selectively adsorb anionic drugs such as benzoic acid and acidic amino acids, and thus can be used as anionic drugs in the body Controlled release carrier. Poly D-lysine (PDL) - methotrexate (MTX) complex without anti-tumor?