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目的探讨米索前列醇对有产后出血倾向患者的防治效果。方法选择2010年1月至2010年12月间产后30 min内出血达150 ml的200例患者,随机分成两组,实验组给予米索前列醇0.6 mg直肠给药,对照组给予缩宫素20 U静脉点滴或宫颈注射。结果实验组产后2 h出血量(298±105)ml,有效率98%;对照组产后2 h出血量(358±95)ml,有效率90%,两组比较差异有统计学意义(P<0.05)。结论米索前列醇直肠给药对防治因子宫收缩乏力引起的产后出血有明显疗效。
Objective To investigate the prevention and treatment of misoprostol in patients with tendency to postpartum hemorrhage. Methods 200 patients with bleeding of 150 ml within 30 min postpartum between January 2010 and December 2010 were randomly divided into two groups. The experimental group was treated with misoprostol 0.6 mg rectally and the control group with 20 U Intravenous or intravenous injection. Results In the experimental group, the amount of hemorrhage (298 ± 105) ml at 2 h postpartum was 98%, while that of the control group was 358 ± 95 ml at 2 h postpartum, with an effective rate of 90%. There was significant difference between the two groups (P < 0.05). Conclusion The administration of misoprostol rectally has a significant effect on the prevention and treatment of postpartum hemorrhage due to uterine atony.