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为成长发育中的人创造安全的劳动条件日益重要。等人的临床卫生学观察表明:在苯的作用下,廿一岁以下的人在血液、骨髓和神经系统方面的改变比成人更早、更明显。根据的资料,未成年动物对致死水平的苯吸入或灌胃耐受性较小。但也有人用经皮试验得出了相反的结论。本文作者之一较早做的实验发现苯在致死剂量水平,使未成年动物较易死亡,在阈剂量水平(成年动物急性阈剂量为1.1毫克/升、白细胞数量增高;未成年动物急性阈剂量为0.1毫克/升、血小板数量增高)一次吸入及最小剂量水平短期反复吸入时,未成年动物较为敏感。但是,对于苯对未成年动物的长期影响研究尚少。本项工作就是为了填补这一空白。
Creating safe working conditions for growing people is increasingly important. The clinical hygiene observations of et al. Showed that changes in blood, bone marrow, and nervous system were earlier and more pronounced in adults under the age of twenty-one under the influence of benzene. According to the information, underage animals on the lethal level of benzene inhalation or gavage less tolerant. However, others have used the transdermal test to reach the opposite conclusion. An earlier experiment by one of the authors found benzene at the lethal dose level, which makes juvenile animals more likely to die. At the threshold dose level (adult animals acute threshold dose of 1.1 mg / l, leukocyte count increase; acute animal acute threshold dose 0.1 mg / l, increased platelet count) Inhalation and minimum dose levels Repeated inhalation, the juvenile animals are more sensitive. However, little is known about the long-term effects of benzene on juvenile animals. This work is to fill this gap.