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目的:探讨治疗全耐药阴沟肠杆菌尿路感染的方法。方法:临床药师参加会诊2006年4月—2008年8月28例全耐药阴沟肠杆菌尿路感染的住院患者,建议采用磷霉素4g+5%葡萄糖250mL,静脉滴注,每天3次,第一次给予磷霉素完毕后30min,立即给予左氧氟沙星0.6g静脉滴注,每天一次。结果:痊愈18例(64.28%),有效5例(17.86%),好转3例(10.71%),无效2例(7.14%),总有效率92.86%。结论:采用左氧氟沙星与磷霉素联合应用治疗全耐药阴沟肠杆菌尿路感染有效,也为治疗全耐药阴沟肠杆菌尿路感染提供新的治疗途径。
Objective: To explore the method of treating all-drug-resistant Enterobacter cloacae urinary tract infection. Methods: Clinical pharmacists participated in the consultation From April 2006 to August 2008, 28 hospitalized patients with full-drug-resistant Enterobacter cloacae urinary tract infection recommended fosfomycin 4g + 5% glucose 250mL, intravenous infusion, 3 times a day, After the first administration of fosfomycin 30min, immediately given levofloxacin 0.6g intravenously, once daily. Results: 18 cases (64.28%) were cured, 5 cases (17.86%) were effective, 3 cases (10.71%) were improved, 2 cases (7.14%) were ineffective, and the total effective rate was 92.86%. Conclusion: The combination of levofloxacin and fosfomycin is effective in treating UR-resistant urinary tract infection of all-drug-resistant Enterobacter cloacae and also provides a new therapeutic approach for the treatment of urinary tract infections with drug-resistant Enterobacter cloacae.