论文部分内容阅读
目的:研究熊去氧胆酸在肾综合征出血热(HFRS)病人体内的抗病毒作用。方法:选择发热期HFRS病人120例,随机分成熊去氧胆酸组(A组)40例,利巴韦林组(B组)40例和时照组(C组)40例,观察病人体温下降时间。结果:入院后体湿下降时间(h)A组51.5±6.3,B组54.6±7.2,C组79.7±12.3。经检验A组及B组与C组比较P<0.05,有显著性差异。结论:熊去氧胆酸在体内具有抗HFRSV的作用。
Objective: To study the antiviral effect of ursodeoxycholic acid in patients with hemorrhagic fever with renal syndrome (HFRS). Methods: One hundred and twenty HFRS patients were randomly divided into 40 cases of ursodeoxycholic acid (group A), 40 cases of ribavirin (group B) and 40 cases of group C (control group). The body temperature Fall time. Results: The time to body wetting after admission (h) was 51.5 ± 6.3 in group A, 54.6 ± 7.2 in group B and 79.7 ± 12.3 in group C, respectively. The test group A and group B and group C compared P <0.05, there are significant differences. Conclusion: Ursodeoxycholic acid has an anti-HFRSV effect in vivo.