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本世纪以来尽管对心肌梗塞作了大量的病理学研究,但到今天,急性心肌梗塞的病理生理学尚未完全澄清。1880年 Winsor 和Weigert 首先阐述了冠状动脉血栓形成和心肌梗塞的关系。1956年 Branwood 和 Mont-gomery 发现,新发生的心肌梗塞中,仅21%的病例其冠状动脉有闭塞性血栓,且许多血栓是在梗塞之后形成的,据此对心肌梗塞是由于冠状动脉血栓所致表示异议。随之,其他病理学者对血栓造成心肌梗塞也产生怀疑。1973年以来大多数病理学研究发现,
Although a large number of pathological studies have been conducted on myocardial infarction since the beginning of this century, the pathophysiology of acute myocardial infarction has not yet been completely elucidated to this day. In 1880 Winsor and Weigert first described the relationship between coronary thrombosis and myocardial infarction. In 1956 Branwood and Montgomery found that in only 21% of new myocardial infarctions, there were occlusive thrombi in the coronary arteries and many thrombi were formed after the infarction, whereby myocardial infarction was due to coronary artery thrombosis To express objection. Following this, other pathologists are also suspicious of thrombus-induced myocardial infarction. Most pathological studies since 1973 found that,