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目的:观察联用莪术油葡萄糖注射液和黄芪注射液治疗肾综合征出血热的临床疗效。方法:将191 例肾综合征出血热患者随机分为2 组,治疗组98 例,采用莪术油葡萄糖注射液250 m l静滴,每日1次,连用2~3 日,黄芪注射液30 m l加入10% 葡萄糖250 m l中静滴,每日1 次,直到恢复期;对照组93 例只采用常规治疗。结果:治疗组治愈84例,好转12 例,越期率为93.9% ,总有效率为98.0% ;对照组治愈64 例,好转13 例,总有效率为82.8% ,越期率为77.4% ,治疗组疗效明显优于对照组(P均< 0.01)。实验室检查指标和临床症状、体征的改善时间治疗组也明显优于对照组(P均< 0.05),且未见任何不良反应。结论:联用莪术油葡萄糖注射液和黄芪注射液是治疗肾综合征出血热的有效方法,值得深入研究和推广应用。
Objective: To observe the curative effect of combination of zedoary turmeric oil glucose injection and astragalus injection on hemorrhagic fever with renal syndrome. Methods: Ninety-one patients with hemorrhagic fever with renal syndrome were randomly divided into two groups. The treatment group received intravenous injection of Curcuma oil and glucose 250 ml once daily for 2-3 days. Radix astragali injection 30 m l added 10% glucose 250 m l in intravenous infusion once a day until the recovery period; 93 cases of the control group only conventional treatment. Results: The treatment group cured 84 cases, improved in 12 cases, the overdue rate was 93.9%, the total effective rate was 98.0%; control group 64 cases cured, improved in 13 cases, the total effective rate was 82.8% The rate of 77.4%, the treatment group was significantly better than the control group (P all <0.01). Laboratory test indicators and clinical symptoms and signs of improvement time treatment group was also significantly better than the control group (P all <0.05), and no adverse reactions. Conclusion: The combination of Curcuma oil glucose injection and Astragalus injection is an effective method for the treatment of hemorrhagic fever with renal syndrome, which deserves further study and application.